Retin-A (tretinoin) has earned the anti-aging reputation and loyalty of many dermatologists simply because, it works! Unlike most beauty product “lofty claims”, there’s proof at the molecular level of a demonstrable skin health improvement in Retin-A use for more than 25 years. First used as an acne treatment, patients soon reported their skin became vibrant and smooth. Retin-A users reported improvements in skin texture, diminished wrinkles, and brown spots. Early studies in 1988 confirmed its anti-aging effects with statistically significant improvements. Skin cells contain retinoid receptors that help regulate how the cell functions. As people age, their cells behave [...]